Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433216 | 0.86 | ALDH1A1 (0.48) | FFAR1LMNATDP1ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL1432917 | 0.85 | ALDH1A1 (0.47) | FFAR1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL23582957 | 0.81 | ALOX15 (0.57) | FFAR1CA2 | |
| SCHEMBL23582938 | 0.81 | PLA2G4B (0.55) | CA2 | |
| SCHEMBL10506137 | 0.80 | MEN1 (0.58) | TDP1KDM4EBLM | |
| SCHEMBL9517796 | 0.79 | POLB (0.54) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL9450347 | 0.79 | MEN1 (0.49) | TDP1BLM | |
| SCHEMBL16254218 | 0.79 | FFAR1 (0.72) | FFAR1CA2 | |
| SCHEMBL6539400 | 0.77 | KMT2A (0.49) | FFAR1TDP1KDM4EBLM | |
| SCHEMBL3371954 | 0.77 | MEN1 (0.51) | TDP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999989-B2 | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R-TECH UENO, LTD. (JP) | 2015-04-07 | — | — | US | disclosed |