SCHEMBL16622232

SCHEMBL16622232

Cc1ccccc1-c1ncc(-c2cc(F)cc(F)c2)nc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
PDGFRB P09619 1/20 0.43
KDR P35968 1/20 0.43
FLT3 P36888 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
KMT2A Q03164 1/20 0.42
ALOX5AP P20292 1/20 0.40
FEN1 P39748 1/20 0.40
ABL1 P00519 1/20 0.39
CKS1B P61024 1/20 0.38
SKP1 P63208 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13072034 0.86 ALOX5AP (0.42) CTDSP1TDP1RAB9ANPC1PDGFRB
SCHEMBL16948795 0.85 RAB9A (0.47) TDP1RAB9ANPC1PDGFRBKDR
SCHEMBL15256054 0.85 ALDH1A1 (0.45) TDP1RAB9ANPC1PDGFRBKDR
SCHEMBL2280864 0.85 TDP1 (0.55) CTDSP1TDP1RAB9ANPC1PDGFRB
SCHEMBL16948794 0.84 RAB9A (0.44) RAB9ANPC1PDGFRBKDRFLT3
SCHEMBL28019522 0.84 RAB9A (0.51) RAB9ANPC1PDGFRBKDRFLT3
SCHEMBL15256059 0.83 ATR (0.52) RAB9ANPC1PDGFRBKDRFLT3
SCHEMBL16622231 0.83 RAB9A (0.40) CTDSP1TDP1RAB9ANPC1PDGFRB
SCHEMBL15256058 0.83 TDP1 (0.50) TDP1RAB9ANPC1PDGFRBKDR
SCHEMBL16622257 0.82 ATR (0.47) TDP1RAB9ANPC1PDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150214484-A1 Organometallic Complex and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-30 US disclosed
US-8999520-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-04-07 US disclosed