Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980171 | 0.94 | KDM4E (0.41) | KDM4EALDH1A1POLBHPGDMAPT | |
| SCHEMBL2705508 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL14985633 | 0.85 | ALDH1A1 (0.50) | KDM4EALDH1A1POLBHPGDMAPT | |
| SCHEMBL52115 | 0.84 | MAPT (0.43) | KDM4EALDH1A1POLBHPGDMAPT | |
| SCHEMBL29590308 | 0.84 | MAPT (0.43) | KDM4EALDH1A1POLBHPGDMAPT | |
| SCHEMBL2149947 | 0.83 | MAPT (0.50) | KDM4EALDH1A1POLBHPGDMAPT | |
| SCHEMBL31537733 | 0.83 | MAPT (0.50) | KDM4EALDH1A1POLBHPGDMAPT | |
| SCHEMBL13707463 | 0.82 | RAB9A (0.42) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL13772192 | 0.82 | LMNA (0.39) | ALDH1A1NPC1RAB9ACSNK2A2CSNK2B | |
| SCHEMBL1609870 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1POLBHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105943-A | 3-substituted thioxanthone compound, preparation method thereof and application of photopolymerization system | 深圳有为技术控股集团有限公司 | 2022-03-01 | — | — | CN | disclosed |
| EP-2857394-A1 | Antiviral compounds | Gilead Pharmasset LLC (US) | 2015-04-08 | — | — | EP | disclosed |