SCHEMBL16622922

SCHEMBL16622922

C=CC(=O)NC(C)(C)C(=O)OCCCCCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
TSHR P16473 6/20 0.39
CYP3A4 P08684 3/20 0.39
EPHX2 P34913 2/20 0.39
ABCC4 O15439 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
LMNA P02545 1/20 0.34
NFKB1 P19838 1/20 0.34
PMP22 Q01453 1/20 0.34
PPARG P37231 6/20 0.33
PPARD Q03181 6/20 0.33
PPARA Q07869 6/20 0.33
GPR84 Q9NQS5 5/20 0.33
HDAC11 Q96DB2 5/20 0.33
HSD17B10 Q99714 2/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
FABP4 P15090 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26478906 0.85 ZDHHC20 (0.46) ALDH1A1TSHRCYP3A4
SCHEMBL16622923 0.85 ALDH1A1 (0.36) ALDH1A1TSHRCYP3A4CYP2C9CYP2C19
SCHEMBL15448777 0.84 DGKA (0.40) ALDH1A1TSHRCYP3A4EPHX2LMNA
SCHEMBL2032975 0.84 TSHR (0.55) ALDH1A1TSHRCYP3A4MAPTCYP2C9
SCHEMBL583346 0.82 TSHR (0.37) ALDH1A1TSHRCYP3A4CYP2C9CYP2C19
SCHEMBL14007854 0.82 TSHR (0.51) ALDH1A1TSHRCYP3A4MAPTCYP2C9
SCHEMBL26478900 0.79 TSHR (0.38) ALDH1A1TSHRCYP3A4CYP2C9CYP2C19
SCHEMBL30780832 0.78 ALDH1A1 (0.52) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL19951574 0.77 ADRA1A (0.49) EPHX2ABCC4MAPT
SCHEMBL19951583 0.77 ADRA1A (0.49) EPHX2ABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2321370-B1 TWO-PART EPOXY-BASED STRUCTURAL ADHESIVES 3M INNOVATIVE PROPERTIES CO (US) 2017-03-15 EP disclosed
EP-2315741-B1 REACTIVE LIQUID MODIFIERS 3M INNOVATIVE PROPERTIES CO (US) 2015-04-08 EP disclosed