SCHEMBL16622954

SCHEMBL16622954

CC1C/C=C/CCc2[nH]cc(CCO)c21

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16622953 0.69 HTR2C (0.33) HTR2C
SCHEMBL14652663 0.55
SCHEMBL7555788 0.54
SCHEMBL13488455 0.53 HTR2A (0.35) CYP2D6HTR2C
SCHEMBL7908817 0.51 KMT2A (0.42)
SCHEMBL14647082 0.51 CES2 (0.30)
Tryptophol SCHEMBL29364545 0.51 HTR2A (0.67) CYP2D6HTR2C
Tryptophol SCHEMBL196126 0.51 HTR2A (0.67) CYP2D6HTR2C
SCHEMBL2990929 0.51 HTR2C (0.38) CYP2D6HTR2C
SCHEMBL28352672 0.51 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2675801-B1 NOVEL PYRAZOLE AND IMIDAZOLE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2015-04-08 EP disclosed