Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | IGLV6-57 | P01721 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118223 | 0.80 | KDM4E (0.62) | KMT2AF2ALDH1A1HPGDGLA | |
| SCHEMBL16623269 | 0.72 | ALDH1A1 (0.42) | KMT2AALDH1A1IGLV6-57HPGDGLA | |
| SCHEMBL16623286 | 0.71 | MAOB (0.56) | KMT2AALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL10337820 | 0.67 | ALDH1A1 (0.68) | KMT2AALDH1A1IGLV6-57HPGDGLA | |
| SCHEMBL20273292 | 0.65 | RAB9A (0.62) | KMT2AF2ALDH1A1IGLV6-57HPGD | |
| SCHEMBL20163089 | 0.64 | KDM4E (0.49) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL25054015 | 0.64 | KMT2A (1.00) | KMT2AF2ALDH1A1IGLV6-57HPGD | |
| SCHEMBL25055364 | 0.64 | KMT2A (0.65) | KMT2AF2ALDH1A1IGLV6-57HPGD | |
| Ammonia Solution, Strong SCHEMBL21835777 | 0.63 | KDM4E (0.48) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL11888139 | 0.63 | KDM4E (0.74) | KMT2AALDH1A1HPGDGLACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857018-A1 | Treatment or prophylaxis of proliferative conditions | University Court of The University of Dundee (GB) | 2015-04-08 | — | — | EP | disclosed |