Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623939 | 0.86 | ALDH1A1 (0.66) | ABCB1MEN1KMT2AABCG2TP53 | |
| Sinensetin SCHEMBL29700880 | 0.83 | ABCB1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 | |
| Sinensetin SCHEMBL29549544 | 0.83 | ABCB1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 | |
| Sinensetin SCHEMBL621101 | 0.83 | ABCB1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL24951027 | 0.82 | ABCB1 (0.64) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL8069155 | 0.81 | ABCB1 (0.82) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL1421602 | 0.80 | ABCB1 (0.79) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL34468184 | 0.79 | CYP1B1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL31238120 | 0.79 | CYP1B1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL3131502 | 0.79 | CYP1B1 (1.00) | ABCB1MEN1KMT2AABCG2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150098926-A1 | Methods of Treating Hepatitis C Virus Infection | THE J. DAVID GLADSTONE INSTITUTES | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150098926-A1 | Methods of Treating Hepatitis C Virus Infection | HAVCR2, LIPC, FABP1 | ABCB1 3420/4885MEN1 4813/4885KMT2A 3148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.