Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12332936 | 0.88 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL12305428 | 0.84 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL16623997 | 0.82 | TSHR (0.39) | TSHRALDH1A1ALOX15 | |
| SCHEMBL13715093 | 0.80 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL16623951 | 0.78 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL22597447 | 0.74 | TSHR (0.39) | TSHR | |
| SCHEMBL16623957 | 0.71 | THRB (0.34) | TSHRALDH1A1ALOX15 | |
| SCHEMBL29009582 | 0.71 | TSHR (0.57) | TSHRALDH1A1 | |
| SCHEMBL8384361 | 0.70 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL1254890 | 0.70 | TSHR (0.55) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052481-B1 | USE OF POLYMERIZABLE STABLE RADICALS FOR REDUCING THE SHRINKAGE STRESS OF DENTAL COMPOSITIONS | DENTSPLY SIRONA INC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-9931280-B2 | Dental composite compositions for reduced shrinkage stress | DENTSPLY SIRONA INC. (US) | 2018-04-03 | — | — | US | disclosed |
| WO-2015051217-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | DENTSPLY INTERNATIONAL INC. (US) | 2015-04-09 | — | — | WO | disclosed |
| US-20150099821-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | DENTSPLY SIRONA INC. | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099821-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | VCL, HSPA4L, GPX4 | TSHR 3714/4885ALDH1A1 2471/4885ALOX15 598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.