Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17993875 | 0.85 | MEN1 (0.55) | HTR1ATRPV1GRIN2BDRD2DRD1 | |
| SCHEMBL17993840 | 0.83 | HTR7 (0.55) | HTR1ATRPV1ACHEDRD2DRD1 | |
| SCHEMBL6369610 | 0.81 | HTR1A (0.71) | HTR1AGRIN2BDRD2DRD1DRD4 | |
| SCHEMBL18034956 | 0.81 | KDM4E (0.66) | TRPV1ACHEGRIN1GRIN2AGRIN2B | |
| SCHEMBL17993835 | 0.80 | KDM4E (0.46) | TRPV1ACHEGRIN1GRIN2AGRIN2B | |
| SCHEMBL25512896 | 0.78 | ACHE (0.52) | TRPV1ACHEGRIN1GRIN2AGRIN2B | |
| SCHEMBL2188030 | 0.78 | ACHE (0.76) | ACHEGRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL21731608 | 0.77 | MEN1 (0.55) | HTR1ATRPV1DRD2DRD1DRD4 | |
| SCHEMBL3886166 | 0.77 | BAZ2B (0.52) | HTR1AACHEGRIN1GRIN2AGRIN2B | |
| SCHEMBL25512689 | 0.77 | L3MBTL1 (0.61) | ACHEGRIN1GRIN2AGRIN2BGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050212-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | 日産化学工業株式会社 | 2015-04-09 | — | — | WO | disclosed |