Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12901520 | 0.89 | GRIN2B (0.47) | GRIN2BKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL12901522 | 0.89 | ENPP2 (0.48) | GRIN2BKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL12901486 | 0.88 | MEN1 (0.54) | GRIN2BKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL12901516 | 0.77 | JAK2 (0.38) | KMT2AMEN1ALDH1A1L3MBTL1HDAC3 | |
| SCHEMBL12901497 | 0.77 | TEAD1 (0.49) | KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL12901515 | 0.76 | CYP3A4 (0.43) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL16624139 | 0.75 | GPR119 (0.35) | KMT2AMEN1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL12901519 | 0.75 | KMT2A (0.34) | KMT2AMEN1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7384158 | 0.74 | KMT2A (0.59) | GRIN2BKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12901552 | 0.74 | MEN1 (0.48) | GRIN2BKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099738-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099738-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, HRH2 | GRIN2B 1025/4885KMT2A 2280/4885MEN1 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.