SCHEMBL16624733

SCHEMBL16624733

COc1cc(C)c(Pc2c(C)cc(C)cc2OC)c(OC)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.42
PTPN1 P18031 2/20 0.41
NQO2 P16083 2/20 0.37
CYP19A1 P11511 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 2/20 0.34
CYP1A2 P05177 1/20 0.34
RAPGEF4 Q8WZA2 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8019923 0.80 ALDH1A1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL10051168 0.75 ACHE (0.46) ACHEPTPN1NQO2CYP19A1CA12
SCHEMBL15488875 0.73 ACHE (0.41) ACHEPTPN1NQO2CYP19A1CA12
SCHEMBL7187825 0.70 CYP3A4 (0.41) NQO2CYP19A1ALDH1A1KDM4ELMNA
SCHEMBL7190082 0.70 CYP3A4 (0.44) NQO2CYP19A1LMNAGAAHPGD
SCHEMBL1486338 0.70 RAPGEF4 (0.43) ACHECA1CA2ALDH1A1KDM4E
SCHEMBL15120000 0.69 ALDH1A1 (0.52) ACHENQO2CYP19A1CA12CA1
SCHEMBL12141429 0.69 ALDH1A1 (0.48) NQO2CYP19A1CA12CA1CA2
SCHEMBL13976591 0.68 CYP2D6 (0.40) ACHEPTPN1CA12CA1CA2
SCHEMBL3318963 0.68 ACHE (0.46) ACHECA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9303101-B2 Catalyst for synthesizing polyolefins THE UNIVERSITY OF TOKYO (JP) 2016-04-05 US disclosed
US-20150099857-A1 CATALYST FOR SYNTHESIZING POLYOLEFINS SHOWA DENKO K.K. (JP) 2015-04-09 US disclosed