SCHEMBL16624921

SCHEMBL16624921

CC(C)=CCCC(C)CCOC(=O)CC(c1ccccc1)C(C)C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.49
NFE2L2 Q16236 1/20 0.39
EPHX2 P34913 1/20 0.37
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
KCNA5 P22460 1/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
TRPV1 Q8NER1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16624907 0.94 ALOX15 (0.45) ALOX15NFE2L2EPHX2ALDH1A1CYP3A4
SCHEMBL16624923 0.92 ALOX15 (0.44) ALOX15ALDH1A1LMNASMN1; SMN2NPSR1
SCHEMBL19070740 0.87 ALOX15 (0.39) ALOX15NFE2L2EPHX2ALDH1A1L3MBTL1
SCHEMBL16624904 0.83 ALOX15 (0.49) ALOX15NFE2L2EPHX2ALDH1A1NPSR1
SCHEMBL16624896 0.82 SLC22A1 (0.42) ALDH1A1CYP3A4LMNASMN1; SMN2NPSR1
SCHEMBL16624909 0.80 TRPV1 (0.57) ALOX15ALDH1A1TRPV1
SCHEMBL585939 0.79 ALOX15 (0.61) ALOX15NFE2L2ALDH1A1LMNATDP1
SCHEMBL5605056 0.79 ALOX15 (0.61) ALOX15NFE2L2ALDH1A1LMNATDP1
SCHEMBL5605059 0.79 ALOX15 (0.61) ALOX15NFE2L2ALDH1A1LMNATDP1
SCHEMBL19071630 0.78 CYP3A4 (0.39) ALDH1A1CYP3A4LMNANPSR1KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2864284-B1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO KGAA (DE) 2017-07-05 EP disclosed
US-9458081-B2 Photolabile pro-fragrances HENKEL AG & CO. KGAA (DE) 2016-10-04 US disclosed
US-9458081-B2 Photolabile pro-fragrances HENKEL AG & CO. KGAA (DE) 2016-10-04 US disclosed
US-20150099809-A1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2015-04-09 US disclosed
US-20150099809-A1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2015-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150099809-A1 PHOTOLABILE PRO-FRAGRANCES TRPA1, PSAP, CRY1 ALOX15 426/4885NFE2L2 3502/4885EPHX2 2141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.