SCHEMBL16624904

SCHEMBL16624904

CC(C)=CCCC(C)CCOC(=O)CC(CC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 1/20 0.40
NFE2L2 Q16236 1/20 0.39
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
F2 P00734 1/20 0.37
EPHX2 P34913 1/20 0.37
PTPN1 P18031 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16624898 0.94 ALOX15 (0.45) ALOX15L3MBTL1ATMALDH1A1NFE2L2
SCHEMBL16624905 0.92 L3MBTL1 (0.54) ALOX15L3MBTL1ATMALDH1A1POLB
SCHEMBL19071779 0.84 ALOX15 (0.44) ALOX15ALDH1A1NFE2L2F2EPHX2
SCHEMBL16624921 0.83 ALOX15 (0.49) ALOX15L3MBTL1ATMALDH1A1NFE2L2
SCHEMBL16624895 0.82 L3MBTL1 (0.55) L3MBTL1ATMALDH1A1POLBHTT
SCHEMBL585939 0.79 ALOX15 (0.61) ALOX15ALDH1A1NFE2L2
SCHEMBL5605056 0.79 ALOX15 (0.61) ALOX15ALDH1A1NFE2L2
SCHEMBL5605059 0.79 ALOX15 (0.61) ALOX15ALDH1A1NFE2L2
SCHEMBL16624907 0.77 ALOX15 (0.45) ALOX15L3MBTL1ALDH1A1NFE2L2NPSR1
SCHEMBL19680576 0.77 ALOX15 (0.51) ALOX15L3MBTL1ATMALDH1A1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2864284-B1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO KGAA (DE) 2017-07-05 EP disclosed
US-9458081-B2 Photolabile pro-fragrances HENKEL AG & CO. KGAA (DE) 2016-10-04 US disclosed
US-9458081-B2 Photolabile pro-fragrances HENKEL AG & CO. KGAA (DE) 2016-10-04 US disclosed
US-20150099809-A1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2015-04-09 US disclosed
US-20150099809-A1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2015-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150099809-A1 PHOTOLABILE PRO-FRAGRANCES TRPA1, PSAP, CRY1 ALOX15 426/4885L3MBTL1 1799/4885ATM 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.