Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MIF | P14174 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175500 | 0.91 | ELANE (0.48) | ALDH1A1MEN1KMT2AMIFCYP3A4 | |
| SCHEMBL15897069 | 0.84 | MEN1 (0.48) | ALDH1A1MEN1KMT2AMIFCYP3A4 | |
| SCHEMBL15897073 | 0.83 | EGFR (0.47) | ALDH1A1MEN1KMT2AMIFCYP3A4 | |
| SCHEMBL3694469 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL38666633 | 0.81 | EGFR (0.48) | ALDH1A1MEN1KMT2AMIFCYP3A4 | |
| SCHEMBL2437722 | 0.79 | EGFR (0.46) | ALDH1A1MEN1KMT2AMIFCYP3A4 | |
| SCHEMBL30230692 | 0.78 | ELANE (0.44) | ALDH1A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL22148204 | 0.78 | ELANE (0.43) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL23961102 | 0.78 | EPHB3 (0.54) | ALDH1A1CYP1A2ELANEPLAUF2 | |
| SCHEMBL23387905 | 0.77 | ELANE (0.41) | ALDH1A1MEN1KMT2AMIFCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431394-A | Pyridazinone derivatives and medical application thereof | 杭州百新生物医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-11993729-B2 | Chemical mechanical polishing composition | BASF SE (DE) | 2024-05-28 | — | — | US | disclosed |
| EP-4061815-B1 | PYRIMIDONE DERIVATIVES CONTAINING TWO FUSED BICYCLIC RINGS | BASF SE (DE) | 2024-03-20 | — | — | EP | disclosed |
| EP-3714012-B1 | CHEMICAL MECHANICAL POLISHING COMPOSITION | BASF SE (DE) | 2023-01-11 | — | — | EP | disclosed |
| US-20220411428-A1 | Pyrimidone Derivatives Containing Two Fused Bicyclic Rings | BASF SE (DE) | 2022-12-29 | — | — | US | disclosed |
| EP-4061815-A1 | PYRIMIDONE DERIVATIVES CONTAINING TWO FUSED BICYCLIC RINGS | BASF SE (DE) | 2022-09-28 | — | — | EP | disclosed |
| US-11420944-B2 | Voltage-dependent t-type calcium channel blocker | NIPPON CHEMIPHAR CO., LTD. (JP) | 2022-08-23 | — | — | US | disclosed |
| CN-114728977-A | Pyrimidone derivatives containing two fused bicyclic rings | 巴斯夫欧洲公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021099240-A1 | PYRIMIDONE DERIVATIVES CONTAINING TWO FUSED BICYCLIC RINGS | BASF SE (DE) | 2021-05-27 | — | — | WO | disclosed |
| US-20210102093-A1 | USE OF A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION FOR POLISHING OF COBALT COMPRISING SUBSTRATES | BASF SE (DE) | 2021-04-08 | — | — | US | disclosed |
| WO-2019101555-A1 | CHEMICAL MECHANICAL POLISHING COMPOSITION | BASF SE (DE) | 2019-05-31 | — | — | WO | disclosed |
| US-20190077767-A1 | VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL BLOCKER | NIPPON CHEMIPHAR CO., LTD. (JP) | 2019-03-14 | — | — | US | disclosed |
| EP-3404021-A1 | VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL INHIBITOR | Nippon Chemiphar Co., Ltd. (JP) | 2018-11-21 | — | — | EP | disclosed |
| EP-3334794-A1 | USE OF A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION FOR POLISHING OF COBALT COMPRISING SUBSTRATES | BASF SE (DE) | 2018-06-20 | — | — | EP | disclosed |
| WO-2017025536-A1 | USE OF A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION FOR POLISHING OF COBALT COMPRISING SUBSTRATES | BASF SE (DE) | 2017-02-16 | — | — | WO | disclosed |
| WO-2015066371-A1 | SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS | FORUM PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |
| EP-2090576-A1 | 6-halo-pyrazolo[1,5-a]pyridines, a process for their preparation and their use as metabotropic glutamate receptor (mGluR) modulators | Merz Pharma GmbH & Co.KGaA (DE) | 2009-08-19 | — | — | EP | disclosed |
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |
| US-20080051409-A1 | Indolizine Carboxamides and Aza and Diaza Derivatives Thereof | SCHWARZ PHARMA AG (DE) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411428-A1 | Pyrimidone Derivatives Containing Two Fused Bicyclic Rings | DDT, DHFR, PFAS | ALDH1A1 526/4885MEN1 3102/4885KMT2A 3514/4885 |
| US-20080051409-A1 | Indolizine Carboxamides and Aza and Diaza Derivatives Thereof | GRIN2A, GRIN2C, GRIN1 | ALDH1A1 459/4885MEN1 1227/4885KMT2A 455/4885 |
| US-11420944-B2 | Voltage-dependent t-type calcium channel blocker | CACNA1I, CACNA1G, CACNA1E | ALDH1A1 3247/4885MEN1 2133/4885KMT2A 1735/4885 |
| US-20190077767-A1 | VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL BLOCKER | CACNA1I, CACNA1G, CACNA1E | ALDH1A1 3220/4885MEN1 1995/4885KMT2A 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.