Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | HTT | P42858 | 2/20 | 0.81 |
| ▸ | PKM | P14618 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 4/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281318 | 0.90 | MEN1 (0.81) | MEN1KMT2AMAPK1HTTPKM | |
| SCHEMBL5078978 | 0.88 | MEN1 (0.79) | MEN1KMT2AMAPK1HTTPKM | |
| SCHEMBL16616459 | 0.85 | MEN1 (0.80) | MEN1KMT2AMAPK1HTTPKM | |
| SCHEMBL16638716 | 0.84 | MEN1 (0.58) | MEN1KMT2AMAPK1HTTPKM | |
| SCHEMBL16616664 | 0.82 | LMNA (0.58) | MEN1KMT2AMAPK1HTTPKM | |
| SCHEMBL846930 | 0.80 | DHODH (0.76) | MEN1KMT2AMAPK1HTTPKM | |
| SCHEMBL30754730 | 0.80 | MEN1 (0.65) | MEN1KMT2AMAPK1HTTPKM | |
| SCHEMBL16627416 | 0.80 | ALDH1A1 (0.55) | MEN1KMT2AMAPK1HTTPKM | |
| SCHEMBL16627389 | 0.79 | MEN1 (0.62) | MEN1KMT2AMAPK1HTTPKM | |
| SCHEMBL16616492 | 0.79 | SMN1; SMN2 (0.55) | MEN1KMT2AMAPK1HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | HCCS, WEE2, WEE1 | MEN1 2511/4885KMT2A 2973/4885MAPK1 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.