Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627632 | 0.87 | APAF1 (0.55) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL16627798 | 0.86 | BRD4 (0.45) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL16627566 | 0.85 | BRD4 (0.44) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL16627812 | 0.85 | DAO (0.48) | ALDH1A1KDM4ELMNARECQLMEN1 | |
| SCHEMBL16627811 | 0.85 | BRD4 (0.44) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL16627648 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4ELMNARECQLMEN1 | |
| SCHEMBL16627649 | 0.82 | APAF1 (0.42) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL16627642 | 0.81 | MEN1 (0.43) | ALDH1A1KDM4ELMNAMAPTGAA | |
| SCHEMBL28599651 | 0.75 | BRD4 (0.54) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL16627799 | 0.73 | BRD4 (0.45) | ALDH1A1KDM4ELMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |