Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | DDO | Q99489 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627798 | 0.90 | BRD4 (0.45) | APAF1CASP3CASP6SENP8SENP7 | |
| SCHEMBL16627566 | 0.89 | BRD4 (0.44) | APAF1CASP3CASP6SENP8SENP7 | |
| SCHEMBL16627811 | 0.89 | BRD4 (0.44) | APAF1CASP3CASP6SENP8SENP7 | |
| SCHEMBL16627812 | 0.89 | DAO (0.48) | APAF1CASP3CASP6SENP8SENP7 | |
| SCHEMBL16627565 | 0.87 | ALDH1A1 (0.56) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL16627649 | 0.87 | APAF1 (0.42) | APAF1CASP3CASP6SENP8SENP7 | |
| SCHEMBL16627648 | 0.87 | KDM4E (0.44) | APAF1CASP3CASP6SENP8SENP7 | |
| SCHEMBL16627642 | 0.85 | MEN1 (0.43) | APAF1CASP3CASP6SENP8SENP7 | |
| SCHEMBL28599651 | 0.81 | BRD4 (0.54) | BRD4ALDH1A1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL10774671 | 0.81 | DAO (0.50) | APAF1CASP3CASP6SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |