Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627632 | 0.85 | APAF1 (0.55) | MEN1KMT2AALDH1A1APAF1CASP3 | |
| SCHEMBL16627641 | 0.84 | MEN1 (0.44) | MEN1KMT2AGAAPKMNPC1 | |
| SCHEMBL16627798 | 0.84 | BRD4 (0.45) | MEN1KMT2AALDH1A1APAF1CASP3 | |
| SCHEMBL16627566 | 0.83 | BRD4 (0.44) | MEN1KMT2AALDH1A1APAF1CASP3 | |
| SCHEMBL16627812 | 0.83 | DAO (0.48) | MEN1KMT2AALDH1A1APAF1CASP3 | |
| SCHEMBL16627811 | 0.83 | BRD4 (0.44) | MEN1KMT2ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL16627648 | 0.81 | KDM4E (0.44) | MEN1KMT2AALDH1A1APAF1CASP3 | |
| SCHEMBL16627565 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AGAANPC1POLB | |
| SCHEMBL16627649 | 0.81 | APAF1 (0.42) | MEN1KMT2AALDH1A1APAF1CASP3 | |
| SCHEMBL16627849 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AGAANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |