Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627798 | 0.91 | BRD4 (0.45) | KDM4ETSHRAPAF1CASP3CASP6 | |
| SCHEMBL16627812 | 0.87 | DAO (0.48) | KDM4ETSHRAPAF1CASP3CASP6 | |
| SCHEMBL16627632 | 0.87 | APAF1 (0.55) | KDM4ETSHRAPAF1CASP3CASP6 | |
| SCHEMBL16627811 | 0.85 | BRD4 (0.44) | KDM4ETSHRAPAF1CASP3CASP6 | |
| SCHEMBL16627651 | 0.85 | BRD4 (0.44) | KDM4ETSHRBRD4DAODDO | |
| SCHEMBL16627566 | 0.85 | BRD4 (0.44) | KDM4ETSHRAPAF1CASP3CASP6 | |
| SCHEMBL16627565 | 0.82 | ALDH1A1 (0.56) | KDM4ETSHRCASP3SENP8SENP7 | |
| SCHEMBL16627649 | 0.82 | APAF1 (0.42) | KDM4ETSHRAPAF1CASP3CASP6 | |
| SCHEMBL16627642 | 0.81 | MEN1 (0.43) | KDM4ETSHRAPAF1CASP3CASP6 | |
| SCHEMBL16627799 | 0.78 | BRD4 (0.45) | KDM4ETSHRBRD4DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |