Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627692 | 0.82 | CNR1 (0.39) | P2RX7CNR1CNR2THRB | |
| SCHEMBL16627874 | 0.78 | P2RX7 (0.41) | P2RX7LMNAALDH1A1MAPTABCG2 | |
| SCHEMBL16627816 | 0.74 | P2RX7 (0.48) | P2RX7KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL16627681 | 0.73 | NPY5R (0.45) | P2RX7KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL16627878 | 0.72 | P2RX7 (0.49) | P2RX7KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL16627691 | 0.71 | AHR (0.42) | KMT2AMEN1POLB | |
| SCHEMBL16627693 | 0.69 | CNR1 (0.39) | P2RX7MAPTCNR1CNR2 | |
| SCHEMBL16627588 | 0.69 | AHR (0.41) | P2RX7KDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL16627665 | 0.65 | SMN1; SMN2 (0.51) | P2RX7KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL16627749 | 0.64 | MEN1 (0.58) | P2RX7LMNAMAPTABCG2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |