Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627693 | 0.88 | CNR1 (0.39) | P2RX7CNR1CNR2MAPTRXFP1 | |
| SCHEMBL16627878 | 0.80 | P2RX7 (0.49) | P2RX7ALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL16627816 | 0.80 | P2RX7 (0.48) | P2RX7ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL16627576 | 0.78 | P2RX7 (0.43) | P2RX7ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL16627669 | 0.77 | MAPT (0.44) | P2RX7LMNACNR1CNR2MAPT | |
| SCHEMBL16627692 | 0.77 | CNR1 (0.39) | P2RX7CNR1CNR2RXFP1 | |
| SCHEMBL16627759 | 0.67 | NPY5R (0.47) | P2RX7ALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL16627823 | 0.67 | NPY5R (0.47) | P2RX7ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL16627665 | 0.67 | SMN1; SMN2 (0.51) | P2RX7ALDH1A1SMN1; SMN2KMT2ACNR1 | |
| SCHEMBL16627681 | 0.65 | NPY5R (0.45) | P2RX7ALDH1A1SMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |