Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627691 | 0.91 | AHR (0.42) | AHRMEN1KMT2APOLBMAOB | |
| SCHEMBL16627681 | 0.81 | NPY5R (0.45) | MEN1KMT2APOLBALDH1A1RXFP1 | |
| SCHEMBL16627650 | 0.80 | AHR (0.56) | AHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16627824 | 0.79 | MEN1 (0.47) | AHRMEN1KMT2APOLBNPC1 | |
| SCHEMBL16627656 | 0.76 | F10 (0.47) | AHRMEN1KMT2APOLBNPC1 | |
| SCHEMBL16627692 | 0.75 | CNR1 (0.39) | MAOBRXFP1P2RX7NPY5R | |
| SCHEMBL16627690 | 0.73 | RXFP1 (0.40) | MEN1KMT2AMAOBNPC1RAB9A | |
| SCHEMBL16627665 | 0.72 | SMN1; SMN2 (0.51) | AHRMEN1KMT2AALDH1A1P2RX7 | |
| SCHEMBL16627759 | 0.71 | NPY5R (0.47) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL16627823 | 0.71 | NPY5R (0.47) | MEN1KMT2APOLBALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |