Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CD40 | P25942 | 3/20 | 0.48 |
| ▸ | CD40LG | P29965 | 3/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627879 | 0.86 | MAPT (0.51) | MEN1KMT2APARP1RXFP1NPC1 | |
| SCHEMBL16627806 | 0.85 | NHERF1 (0.49) | MEN1KMT2APOLBPARP1RXFP1 | |
| SCHEMBL16627753 | 0.80 | ABCG2 (0.51) | MEN1KMT2APOLBPARP1DUSP3 | |
| SCHEMBL16627819 | 0.79 | BRD4 (0.54) | MEN1KMT2APOLBPARP1RXFP1 | |
| SCHEMBL16627749 | 0.78 | MEN1 (0.58) | MEN1KMT2APOLBHDAC6ABCG2 | |
| SCHEMBL16627818 | 0.77 | RXFP1 (0.53) | MEN1KMT2APOLBPARP1RXFP1 | |
| SCHEMBL7372420 | 0.77 | KMT2A (0.71) | MEN1KMT2APOLBP2RY2GPR17 | |
| SCHEMBL10940496 | 0.77 | KMT2A (0.71) | MEN1KMT2APOLBP2RY2GPR17 | |
| SCHEMBL16627678 | 0.76 | PARP14 (0.52) | MEN1KMT2APOLBRXFP1LMNA | |
| SCHEMBL16627822 | 0.75 | MAPT (0.58) | MEN1KMT2APOLBABCG2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |