Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CD40 | P25942 | 1/20 | 0.47 |
| ▸ | CD40LG | P29965 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627749 | 0.89 | MEN1 (0.58) | ABCG2MEN1KMT2AMAPTPOLB | |
| SCHEMBL16627814 | 0.87 | F10 (0.48) | MEN1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL16627656 | 0.85 | F10 (0.47) | MEN1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL16627754 | 0.85 | RAB9A (0.49) | ABCG2MEN1KMT2AMAPTPOLB | |
| SCHEMBL16627803 | 0.85 | F10 (0.47) | MEN1KMT2AMAPTRXFP1F10 | |
| SCHEMBL16627585 | 0.80 | MEN1 (0.52) | ABCG2MEN1KMT2AMAPTPOLB | |
| SCHEMBL16627824 | 0.75 | MEN1 (0.47) | MEN1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL16627877 | 0.75 | MAPT (0.47) | MEN1KMT2AMAPTPOLBF10 | |
| SCHEMBL10940496 | 0.75 | KMT2A (0.71) | MEN1KMT2AMAPTPOLBP2RY2 | |
| SCHEMBL7372420 | 0.75 | KMT2A (0.71) | MEN1KMT2AMAPTPOLBP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |