Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PRSS12 | P56730 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627818 | 0.91 | RXFP1 (0.53) | MAPTKMT2AMEN1PARP1RXFP1 | |
| SCHEMBL16627806 | 0.88 | NHERF1 (0.49) | MAPTGAAKMT2AKDM4EMEN1 | |
| SCHEMBL16627876 | 0.87 | RXFP1 (0.44) | MAPTKMT2AKDM4EMEN1RXFP1 | |
| SCHEMBL16627585 | 0.86 | MEN1 (0.52) | MAPTGAAKMT2AKDM4EMEN1 | |
| SCHEMBL16627819 | 0.82 | BRD4 (0.54) | MAPTKMT2AMEN1PARP1RXFP1 | |
| SCHEMBL16627678 | 0.79 | PARP14 (0.52) | MAPTGAAKMT2AKDM4EMEN1 | |
| SCHEMBL16627814 | 0.78 | F10 (0.48) | MAPTGAAKMT2AMEN1F10 | |
| SCHEMBL16627828 | 0.77 | PARP14 (0.52) | MAPTGAAKMT2AKDM4EMEN1 | |
| SCHEMBL16627877 | 0.76 | MAPT (0.47) | MAPTKMT2AKDM4EMEN1KDR | |
| SCHEMBL4168784 | 0.74 | KMT2A (0.65) | MAPTGAAKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |