Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13737524 | 0.84 | P2RX4 (0.59) | P2RX4KMT2AHDAC1SMN1; SMN2POLB | |
| SCHEMBL16627618 | 0.84 | P2RX4 (0.55) | P2RX4KMT2AHDAC1SMN1; SMN2POLB | |
| SCHEMBL16627617 | 0.80 | DCTPP1 (0.60) | P2RX4KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL16627570 | 0.77 | P2RX7 (0.52) | P2RX4KMT2AHDAC1POLBGAA | |
| SCHEMBL25252402 | 0.75 | P2RX4 (0.51) | P2RX4KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL14160793 | 0.75 | P2RX4 (1.00) | P2RX4KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL30557006 | 0.74 | P2RX4 (0.67) | P2RX4KMT2AHDAC1SMN1; SMN2POLB | |
| SCHEMBL24138327 | 0.74 | PDE5A (0.54) | P2RX4KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL31138328 | 0.74 | PDE5A (0.54) | P2RX4KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL18356958 | 0.74 | P2RX4 (0.82) | P2RX4KMT2ASMN1; SMN2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |