Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627606 | 0.80 | P2RX4 (0.59) | P2RX4KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL13737524 | 0.80 | P2RX4 (0.59) | P2RX4KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL16627805 | 0.79 | CCR2 (0.54) | DCTPP1P2RX4KMT2APOLBGAA | |
| SCHEMBL16627618 | 0.77 | P2RX4 (0.55) | P2RX4KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL3287293 | 0.77 | DCTPP1 (0.58) | DCTPP1P2RX4KMT2ASMN1; SMN2MAPT | |
| SCHEMBL17671362 | 0.75 | DCTPP1 (1.00) | DCTPP1P2RX4SMN1; SMN2POLBGAA | |
| SCHEMBL17671384 | 0.75 | DCTPP1 (0.79) | DCTPP1P2RX4KMT2ASMN1; SMN2POLB | |
| SCHEMBL27946553 | 0.74 | KMT2A (0.73) | P2RX4KMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL17671330 | 0.74 | DCTPP1 (0.76) | DCTPP1P2RX4KMT2ASMN1; SMN2POLB | |
| SCHEMBL16131554 | 0.73 | DCTPP1 (0.57) | DCTPP1P2RX4KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |