Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627606 | 0.84 | P2RX4 (0.59) | P2RX4HDAC1KMT2APOLBGAA | |
| SCHEMBL13737524 | 0.81 | P2RX4 (0.59) | P2RX4HDAC1KMT2APOLBGAA | |
| SCHEMBL16627617 | 0.77 | DCTPP1 (0.60) | P2RX4KMT2APOLBGAAMAPK1 | |
| SCHEMBL27946553 | 0.75 | KMT2A (0.73) | P2RX4HDAC1KMT2APOLBGAA | |
| SCHEMBL16627628 | 0.74 | P2RX7 (0.67) | P2RX4HDAC1SMN1; SMN2HDAC11HDAC8 | |
| SCHEMBL16627629 | 0.74 | P2RX7 (0.60) | P2RX4HDAC1KMT2AHDAC11HDAC8 | |
| SCHEMBL16627913 | 0.73 | P2RX7 (0.52) | P2RX4HDAC1KMT2AHDAC11HDAC8 | |
| SCHEMBL16627911 | 0.73 | P2RX7 (0.51) | P2RX4HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL16627863 | 0.73 | P2RX7 (0.49) | P2RX4HDAC1POLBSMN1; SMN2HDAC11 | |
| SCHEMBL25252402 | 0.72 | P2RX4 (0.51) | P2RX4KMT2APOLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |