Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627614 | 0.89 | PADI4 (0.39) | PADI4BTKALDH1A1POLBKDM4E | |
| SCHEMBL16627855 | 0.71 | KDM4E (0.40) | ALDH1A1KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL16627845 | 0.71 | KDM4E (0.39) | ALDH1A1POLBKDM4EMAPTHSP90AA1 | |
| SCHEMBL16627854 | 0.70 | KDM4E (0.39) | ALDH1A1KDM4ENPC1RXFP1HSP90AA1 | |
| SCHEMBL16627876 | 0.67 | RXFP1 (0.44) | POLBKDM4ENPC1RXFP1MAOB | |
| SCHEMBL16627597 | 0.64 | KMT2A (0.48) | PADI4ALDH1A1KDM4ENPC1RXFP1 | |
| SCHEMBL16627896 | 0.63 | PARP1 (0.40) | ALDH1A1KDM4ENPC1RXFP1MAPT | |
| SCHEMBL3644717 | 0.63 | MAOB (0.56) | PADI4ALDH1A1POLBKDM4EMAOB | |
| SCHEMBL16627895 | 0.62 | MEN1 (0.58) | PADI4ALDH1A1KDM4ERXFP1MAOB | |
| SCHEMBL16627787 | 0.62 | PARP14 (0.47) | ALDH1A1KDM4ENPC1RXFP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |