Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627818 | 0.88 | RXFP1 (0.53) | RXFP1BRAFTP53MMP2MMP9 | |
| SCHEMBL16627879 | 0.87 | MAPT (0.51) | RXFP1BRAFTP53MAPTKDM4E | |
| SCHEMBL16627819 | 0.80 | BRD4 (0.54) | RXFP1MAPTMEN1KMT2ABRD4 | |
| SCHEMBL16627690 | 0.79 | RXFP1 (0.40) | RXFP1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL16627806 | 0.76 | NHERF1 (0.49) | RXFP1TP53MAPTKDM4EMEN1 | |
| SCHEMBL16627766 | 0.74 | NPC1 (0.49) | MEN1KMT2AMAOBRAB9ANPC1 | |
| SCHEMBL16627585 | 0.74 | MEN1 (0.52) | RXFP1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL16627635 | 0.74 | KMT2A (0.38) | RXFP1TP53MAPTKDM4EMEN1 | |
| SCHEMBL16627875 | 0.71 | ADORA3 (0.53) | RXFP1TP53MMP2MMP9MMP8 | |
| SCHEMBL26417175 | 0.69 | MEN1 (0.57) | TP53MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |