Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627787 | 0.83 | PARP14 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL16627783 | 0.82 | PARP14 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL16627626 | 0.81 | MAPT (0.47) | KDM4EALDH1A1MAPTLMNARAB9A | |
| SCHEMBL16627784 | 0.80 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL16627893 | 0.77 | KMT2A (0.51) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL16627845 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL15200885 | 0.70 | TP53 (0.44) | KDM4EALDH1A1MAPTLMNAHTT | |
| SCHEMBL16627855 | 0.70 | KDM4E (0.40) | PARP1KDM4EALDH1A1CYP2C9HPGD | |
| SCHEMBL16627854 | 0.69 | KDM4E (0.39) | PARP1KDM4EALDH1A1RXFP1CYP2C9 | |
| SCHEMBL16627777 | 0.68 | SMN1; SMN2 (0.58) | KDM4EALDH1A1LMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |