Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 5/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627610 | 0.89 | PADI4 (0.38) | PADI4BTKHSP90AA1PELI1KDM4E | |
| SCHEMBL16627845 | 0.73 | KDM4E (0.39) | HSP90AA1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL16627855 | 0.73 | KDM4E (0.40) | HSP90AA1KDM4EALDH1A1HSP90AB1 | |
| SCHEMBL16627854 | 0.72 | KDM4E (0.39) | HSP90AA1KDM4EALDH1A1NPC1RXFP1 | |
| SCHEMBL16627680 | 0.71 | PARP14 (0.48) | HSP90AA1KDM4EALDH1A1HSP90AB1MEN1 | |
| SCHEMBL9182411 | 0.67 | KDM4E (0.52) | KDM4EALDH1A1POLBMAPTNPC1 | |
| SCHEMBL9302896 | 0.65 | HSP90AA1 (0.46) | HSP90AA1PDK2PDK1PDK3PDK4 | |
| SCHEMBL16627896 | 0.65 | PARP1 (0.40) | KDM4EALDH1A1MAPTNPC1RXFP1 | |
| SCHEMBL3644717 | 0.65 | MAOB (0.56) | PADI4KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL16627895 | 0.64 | MEN1 (0.58) | PADI4KDM4EALDH1A1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |