Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627855 | 0.82 | KDM4E (0.40) | KDM4EPARP14ALDH1A1CYP2C9HPGD | |
| SCHEMBL16627680 | 0.81 | PARP14 (0.48) | KDM4ENPSR1PARP14ALDH1A1CYP2C9 | |
| SCHEMBL16627854 | 0.81 | KDM4E (0.39) | KDM4EPARP14ALDH1A1CYP2C9HPGD | |
| SCHEMBL16627840 | 0.77 | MEN1 (0.46) | KDM4ETSHRALDH1A1HPGDGAA | |
| SCHEMBL16627614 | 0.73 | PADI4 (0.39) | KDM4EPOLBALDH1A1MAPTHSP90AA1 | |
| SCHEMBL16627896 | 0.72 | PARP1 (0.40) | KDM4ENPSR1HTTPARP14ALDH1A1 | |
| SCHEMBL16627787 | 0.71 | PARP14 (0.47) | KDM4ENPSR1TSHRPARP14ALDH1A1 | |
| SCHEMBL16627610 | 0.71 | PADI4 (0.38) | KDM4EPOLBALDH1A1MAPTHSP90AA1 | |
| SCHEMBL16627783 | 0.71 | PARP14 (0.47) | KDM4ENPSR1POLBPARP14ALDH1A1 | |
| SCHEMBL16627784 | 0.69 | ALDH1A1 (0.46) | KDM4ENPSR1POLBPARP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |