Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627717 | 0.91 | P2RX7 (0.48) | P2RX7KMT2AP2RX4HDAC1MCL1 | |
| SCHEMBL16627673 | 0.91 | P2RX7 (0.48) | P2RX7P2RX4HDAC1MCL1HDAC11 | |
| SCHEMBL16627865 | 0.87 | P2RX7 (0.58) | P2RX7KMT2AP2RX4P2RX3MEN1 | |
| SCHEMBL16627911 | 0.78 | P2RX7 (0.51) | P2RX7P2RX4HDAC1HDAC11HDAC8 | |
| SCHEMBL16627866 | 0.77 | P2RX7 (0.49) | P2RX7KMT2AP2RX4HDAC1HDAC11 | |
| SCHEMBL16627913 | 0.75 | P2RX7 (0.52) | P2RX7KMT2AP2RX4HDAC1HDAC11 | |
| SCHEMBL16627863 | 0.74 | P2RX7 (0.49) | P2RX7P2RX4HDAC1HDAC11HDAC8 | |
| SCHEMBL16627864 | 0.74 | P2RX7 (0.60) | P2RX7P2RX4HDAC1MAPTTP53 | |
| SCHEMBL16627628 | 0.73 | P2RX7 (0.67) | P2RX7P2RX4HDAC1HDAC11HDAC8 | |
| SCHEMBL16627910 | 0.70 | P2RX7 (0.58) | P2RX7P2RX4HDAC1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |