Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.54 |
| ▸ | CNR2 | P34972 | 5/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627834 | 0.89 | KMT2A (0.53) | CNR1CNR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL16627830 | 0.82 | CNR1 (0.47) | CNR1CNR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL16627770 | 0.82 | KMT2A (0.57) | AKR1B10AKR1B1SLC6A5KMT2AMEN1 | |
| SCHEMBL16627676 | 0.80 | P2RX4 (0.52) | CNR1CNR2KMT2AMEN1AHR | |
| SCHEMBL27806397 | 0.79 | P2RX4 (0.51) | CNR1CNR2KMT2AMEN1LMNA | |
| SCHEMBL16627707 | 0.77 | P2RX7 (0.57) | KMT2AMEN1ALDH1A1HDAC1HDAC8 | |
| SCHEMBL16627829 | 0.77 | KMT2A (0.49) | CNR1CNR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL16627697 | 0.73 | CNR2 (0.49) | CNR1CNR2KMT2AMEN1AHR | |
| SCHEMBL8548802 | 0.73 | NPC1 (0.72) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL28489579 | 0.73 | NPC1 (0.72) | KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |