Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | CNR2 | P34972 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627581 | 0.89 | CNR1 (0.54) | KMT2AKDM4ELMNACNR1CNR2 | |
| SCHEMBL16627830 | 0.86 | CNR1 (0.47) | KMT2AKDM4ETP53POLBSMN1; SMN2 | |
| SCHEMBL16627770 | 0.85 | KMT2A (0.57) | KMT2AKDM4ETP53POLBSMN1; SMN2 | |
| SCHEMBL16627676 | 0.80 | P2RX4 (0.52) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| SCHEMBL16627829 | 0.80 | KMT2A (0.49) | KMT2AKDM4ETP53POLBSMN1; SMN2 | |
| SCHEMBL27806397 | 0.79 | P2RX4 (0.51) | KMT2ATP53POLBSMN1; SMN2LMNA | |
| SCHEMBL24273389 | 0.77 | CHRM1 (0.58) | KMT2ATP53MAPTLMNA | |
| SCHEMBL16627707 | 0.77 | P2RX7 (0.57) | KMT2AKDM4ETP53POLBSMN1; SMN2 | |
| SCHEMBL16627697 | 0.77 | CNR2 (0.49) | KMT2AKDM4ETP53POLBMAPT | |
| SCHEMBL25474382 | 0.76 | KMT2A (0.62) | KMT2AKDM4EPOLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |