Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627698 | 0.89 | CNR2 (0.47) | CNR2CNR1AHR | |
| SCHEMBL16627881 | 0.80 | SMN1; SMN2 (0.50) | CNR2CNR1KDM4EKMT2AMEN1 | |
| SCHEMBL16627837 | 0.80 | NR1H2 (0.41) | CNR2CNR1KDM4EKMT2ATP53 | |
| SCHEMBL16627836 | 0.79 | NR1H2 (0.42) | CNR2CNR1KDM4EKMT2ATP53 | |
| SCHEMBL16627841 | 0.78 | NR1H2 (0.41) | CNR2CNR1KDM4EKMT2ATP53 | |
| SCHEMBL16627770 | 0.77 | KMT2A (0.57) | KDM4EKMT2ATP53MAPTMEN1 | |
| SCHEMBL16627834 | 0.77 | KMT2A (0.53) | CNR2CNR1KDM4EKMT2AFPR2 | |
| SCHEMBL5438302 | 0.75 | KMT2A (0.55) | KDM4EKMT2ATP53MAPTMEN1 | |
| SCHEMBL25474382 | 0.73 | KMT2A (0.62) | KDM4EKMT2AMAPTMEN1POLB | |
| SCHEMBL16627581 | 0.73 | CNR1 (0.54) | CNR2CNR1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |