Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627836 | 0.86 | NR1H2 (0.42) | NR1H2L3MBTL1NPC1EGLN1CNR2 | |
| SCHEMBL16627837 | 0.85 | NR1H2 (0.41) | NR1H2L3MBTL1NPC1EGLN1CNR2 | |
| SCHEMBL16627714 | 0.79 | SMN1; SMN2 (0.43) | NR1H2L3MBTL1NPC1CNR2CNR1 | |
| SCHEMBL16627884 | 0.78 | SMN1; SMN2 (0.43) | NR1H2L3MBTL1CNR2CNR1KDM4E | |
| SCHEMBL16627883 | 0.78 | SMN1; SMN2 (0.43) | NR1H2L3MBTL1CNR2CNR1KDM4E | |
| SCHEMBL16627881 | 0.78 | SMN1; SMN2 (0.50) | L3MBTL1NPC1CNR2CNR1KDM4E | |
| SCHEMBL16627697 | 0.78 | CNR2 (0.49) | EGLN1CNR2CNR1KDM4EMAPT | |
| SCHEMBL16627698 | 0.77 | CNR2 (0.47) | NR1H2CNR2CNR1 | |
| SCHEMBL16627882 | 0.75 | KMT2A (0.43) | KDM4EMAPTMEN1KMT2AGAA | |
| SCHEMBL16627695 | 0.70 | HTT (0.45) | L3MBTL1NPC1CNR2CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |