Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627790 | 0.82 | P2RX7 (0.70) | P2RX7MAPTSMN1; SMN2KMT2APOLB | |
| SCHEMBL16627791 | 0.78 | P2RX7 (0.69) | P2RX7MAPTKMT2ANPC1RAB9A | |
| SCHEMBL16627581 | 0.77 | CNR1 (0.54) | KMT2AMEN1KDM4EALDH1A1HDAC1 | |
| SCHEMBL16627834 | 0.77 | KMT2A (0.53) | MAPTSMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL16627637 | 0.75 | NPC1 (0.48) | MAPTSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL16627878 | 0.73 | P2RX7 (0.49) | P2RX7MAPTSMN1; SMN2KMT2APOLB | |
| SCHEMBL16627736 | 0.72 | NPC1 (0.50) | MAPTSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL16627655 | 0.72 | NPC1 (0.52) | MAPTSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL16627816 | 0.72 | P2RX7 (0.48) | P2RX7MAPTSMN1; SMN2POLBKDM4E | |
| SCHEMBL16627684 | 0.72 | PLCG2 (0.48) | SMN1; SMN2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |