Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627791 | 0.83 | P2RX7 (0.69) | P2RX7KMT2AMAPT | |
| SCHEMBL16627789 | 0.82 | P2RX7 (0.83) | P2RX7MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL16627707 | 0.82 | P2RX7 (0.57) | P2RX7MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16627902 | 0.80 | P2RX7 (1.00) | P2RX7ALDH1A1SMN1; SMN2LMNACYP3A4 | |
| SCHEMBL16627903 | 0.79 | P2RX7 (0.81) | P2RX7MAPT | |
| SCHEMBL16627793 | 0.78 | P2RX7 (0.80) | P2RX7SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL16627901 | 0.77 | P2RX7 (0.78) | P2RX7MAPT | |
| SCHEMBL16627794 | 0.76 | P2RX7 (0.77) | P2RX7SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL16627878 | 0.75 | P2RX7 (0.49) | P2RX7MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL18356953 | 0.74 | P2RX4 (0.52) | P2RX7MEN1KMT2APLA2G2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |