Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627696 | 0.86 | LMNA (0.49) | CNR1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16627695 | 0.86 | HTT (0.45) | CNR1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16627833 | 0.78 | TDP1 (0.50) | HTTSMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL16627881 | 0.77 | SMN1; SMN2 (0.50) | CNR1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16627590 | 0.76 | NPC1 (0.49) | HTTSMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL2165925 | 0.73 | EPHX2 (0.69) | SMN1; SMN2KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL5434666 | 0.70 | ELANE (0.55) | CNR1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16627836 | 0.70 | NR1H2 (0.42) | CNR1HTTKMT2AMEN1CNR2 | |
| SCHEMBL16236935 | 0.68 | MAOB (0.55) | CNR1SMN1; SMN2KMT2AMEN1CNR2 | |
| SCHEMBL16627714 | 0.67 | SMN1; SMN2 (0.43) | CNR1HTTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |