Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627590 | 0.80 | NPC1 (0.49) | RXFP1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16627696 | 0.80 | LMNA (0.49) | L3MBTL1THRBRXFP1MEN1KMT2A | |
| SCHEMBL16627714 | 0.79 | SMN1; SMN2 (0.43) | TDP1L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL16627712 | 0.78 | CNR1 (0.47) | L3MBTL1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16627881 | 0.78 | SMN1; SMN2 (0.50) | L3MBTL1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16627883 | 0.78 | SMN1; SMN2 (0.43) | TDP1L3MBTL1RXFP1KDM4EHTT | |
| SCHEMBL16627884 | 0.78 | SMN1; SMN2 (0.43) | TDP1L3MBTL1KDM4EALDH1A1HTT | |
| SCHEMBL16627695 | 0.78 | HTT (0.45) | L3MBTL1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16627882 | 0.75 | KMT2A (0.43) | RXFP1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL5441836 | 0.71 | ELANE (0.54) | TDP1L3MBTL1MEN1KMT2APOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |