Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627712 | 0.86 | CNR1 (0.47) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL16627695 | 0.85 | HTT (0.45) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL16627833 | 0.80 | TDP1 (0.50) | LMNASMN1; SMN2HTTRXFP1THRB | |
| SCHEMBL16627881 | 0.78 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL16627590 | 0.77 | NPC1 (0.49) | SMN1; SMN2HTTRXFP1TP53GAA | |
| SCHEMBL16627835 | 0.76 | CNR1 (0.48) | LMNARXFP1TP53KMT2AMEN1 | |
| SCHEMBL5434666 | 0.69 | ELANE (0.55) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL16627714 | 0.69 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL16627884 | 0.68 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2HTTTP53CNR1 | |
| SCHEMBL16627883 | 0.68 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2HTTRXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |