Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627881 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AKDM4ECNR1 | |
| SCHEMBL16627884 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4ECNR1CNR2PDE10A | |
| SCHEMBL16627883 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4ECNR1CNR2PDE10A | |
| SCHEMBL16627882 | 0.88 | KMT2A (0.43) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16627836 | 0.80 | NR1H2 (0.42) | NPC1KDM4ECNR1CNR2NR1H2 | |
| SCHEMBL16627837 | 0.79 | NR1H2 (0.41) | NPC1KDM4ECNR1CNR2NR1H2 | |
| SCHEMBL16627841 | 0.79 | NR1H2 (0.41) | NPC1RAB9AKDM4ECNR1CNR2 | |
| SCHEMBL16627833 | 0.79 | TDP1 (0.50) | SMN1; SMN2NPC1RAB9AKDM4ELMNA | |
| SCHEMBL16627835 | 0.73 | CNR1 (0.48) | CNR1CNR2POLBLMNAMAPT | |
| SCHEMBL16627697 | 0.71 | CNR2 (0.49) | KDM4ECNR1CNR2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |