Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627872 | 0.86 | CNR1 (0.52) | MAPTL3MBTL1CDC25BMEN1KMT2A | |
| SCHEMBL16627870 | 0.86 | DRD2 (0.45) | MAPTL3MBTL1CDC25BMEN1KMT2A | |
| SCHEMBL16627871 | 0.86 | KDM4E (0.47) | MAPTCDC25BKDM4EALDH1A1HPGD | |
| SCHEMBL16627733 | 0.84 | MAPT (0.45) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14980579 | 0.81 | KDM4E (0.50) | MAPTL3MBTL1CDC25BMEN1KMT2A | |
| SCHEMBL16627734 | 0.77 | MEN1 (0.58) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL34468745 | 0.76 | KMT2A (0.65) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16627856 | 0.76 | BRD4 (0.54) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL7809286 | 0.75 | LMNA (0.52) | CDC25BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1367650 | 0.74 | IL4I1 (0.49) | IDH1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |