Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | PDE9A | O76083 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CLPP | Q16740 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627735 | 0.88 | MEN1 (0.47) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL16627733 | 0.81 | MAPT (0.45) | MEN1KMT2AKDM4EKDRALDH1A1 | |
| SCHEMBL16627872 | 0.77 | CNR1 (0.52) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL16627870 | 0.77 | DRD2 (0.45) | MEN1KMT2ANPC1KDM4EKDR | |
| SCHEMBL16627871 | 0.77 | KDM4E (0.47) | NPC1RAB9AKDM4EKDRPDE9A | |
| SCHEMBL16627873 | 0.77 | IDH1 (0.46) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL16627728 | 0.73 | KDM4E (0.56) | LMNANPC1RAB9ATSHRKDM4E | |
| SCHEMBL16627856 | 0.70 | BRD4 (0.54) | LMNATSHRKDM4EKDRALDH1A1 | |
| SCHEMBL9672474 | 0.70 | MAPT (0.63) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL4079906 | 0.70 | FYN (0.61) | MEN1KMT2ALMNATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |