Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.44 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627735 | 0.78 | MEN1 (0.47) | MEN1KMT2AKDM4ETAAR1IL4I1 | |
| SCHEMBL16627809 | 0.77 | BRD4 (0.51) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL4780633 | 0.74 | AURKA (0.49) | MEN1KMT2AKDM4EMAPTTAAR1 | |
| SCHEMBL16627856 | 0.74 | BRD4 (0.54) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL16627733 | 0.74 | MAPT (0.45) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL7591960 | 0.74 | MMP2 (0.50) | KDM4EMAPTGPR84ALDH1A1GAA | |
| SCHEMBL16627873 | 0.73 | IDH1 (0.46) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL16627872 | 0.73 | CNR1 (0.52) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL16627871 | 0.73 | KDM4E (0.47) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL13664577 | 0.73 | TAAR1 (0.62) | MEN1KMT2AKDM4EMAPTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |