Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627803 | 0.93 | F10 (0.47) | RAB9AF10NPC1ALDH1A1GAA | |
| SCHEMBL16627814 | 0.89 | F10 (0.48) | RAB9AF10NPC1ALDH1A1GAA | |
| SCHEMBL16627656 | 0.87 | F10 (0.47) | RAB9AF10NPC1ALDH1A1GAA | |
| SCHEMBL16627753 | 0.85 | ABCG2 (0.51) | RAB9AF10NPC1POLBMAPT | |
| SCHEMBL16627880 | 0.83 | HDAC1 (0.47) | F10ALDH1A1POLBHDAC1MAPT | |
| SCHEMBL16627824 | 0.82 | MEN1 (0.47) | NPC1ALDH1A1GAAPOLBAHR | |
| SCHEMBL16627877 | 0.80 | MAPT (0.47) | F10ALDH1A1POLBHDAC1MAPT | |
| SCHEMBL16627749 | 0.78 | MEN1 (0.58) | RAB9ANPC1LMNAPOLBMAPT | |
| SCHEMBL19234504 | 0.75 | NPC1 (0.72) | RAB9ANPC1ALDH1A1GAALMNA | |
| SCHEMBL13754018 | 0.75 | NPC1 (0.72) | RAB9ANPC1ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |