Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627877 | 0.90 | MAPT (0.47) | HDAC1MAPTTP53POLBTDP1 | |
| SCHEMBL16627803 | 0.89 | F10 (0.47) | HDAC1MAPTTP53P2RX7F10 | |
| SCHEMBL16627749 | 0.87 | MEN1 (0.58) | MAPTTP53POLBTDP1P2RX7 | |
| SCHEMBL16627685 | 0.86 | MEN1 (0.47) | MAPTTP53POLBP2RX7F10 | |
| SCHEMBL16627754 | 0.83 | RAB9A (0.49) | HDAC1MAPTPOLBP2RX7F10 | |
| SCHEMBL16627823 | 0.83 | NPY5R (0.47) | MAPTTP53POLBTDP1P2RX7 | |
| SCHEMBL16627814 | 0.77 | F10 (0.48) | MAPTTP53POLBF10MEN1 | |
| SCHEMBL16627806 | 0.77 | NHERF1 (0.49) | MAPTTP53POLBF10MEN1 | |
| SCHEMBL16627656 | 0.76 | F10 (0.47) | MAPTPOLBF10MEN1ALDH1A1 | |
| SCHEMBL16627753 | 0.74 | ABCG2 (0.51) | MAPTPOLBF10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |