Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627814 | 0.89 | F10 (0.48) | F10AHRMAPTNPC1MEN1 | |
| SCHEMBL16627754 | 0.87 | RAB9A (0.49) | F10AHRMAPTNPC1MEN1 | |
| SCHEMBL16627803 | 0.87 | F10 (0.47) | F10AHRMAPTNPC1MEN1 | |
| SCHEMBL16627753 | 0.85 | ABCG2 (0.51) | F10MAPTNPC1MEN1KMT2A | |
| SCHEMBL16627877 | 0.77 | MAPT (0.47) | F10MAPTMEN1KMT2APRSS12 | |
| SCHEMBL16627824 | 0.77 | MEN1 (0.47) | AHRMAPTNPC1MEN1KMT2A | |
| SCHEMBL16627588 | 0.76 | AHR (0.41) | AHRNPC1MEN1KMT2ARXFP1 | |
| SCHEMBL16627880 | 0.76 | HDAC1 (0.47) | F10MAPTMEN1KMT2APOLB | |
| SCHEMBL16627749 | 0.74 | MEN1 (0.58) | MAPTNPC1MEN1KMT2ARXFP1 | |
| SCHEMBL16627752 | 0.73 | AHR (0.81) | AHRMAPTNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |